Examined Causal mechanisms behind intergenerational transmission of nutritional choices and their association with metabolic risk indicators
Category: Project
The Medical Research Council of the United Kingdom (MRC-UK) launched ‘Confidence in Global Mental Health Research: Institutional “pump-priming” awards to develop new opportunities in Global Mental Health Research’ in July 2017 . Through these awards, the MRC-UK offered a one year grant opportunity to lay the grounds for future large scale, multi-disciplinary, cross-country global mental health research. The aim being to study mental health issues which are of primary relevance in low and middle income countries (LMICs). The initial focus of the MRC grant was the aetiology of mental illness and the impact of challenges to early brain development on mental health.
In 2013, SLTR partnered with an international research project: Collection of a Collaborative Database CODATwins project (CODAT) identifying 67 twin projects in the world which included 54 twin cohorts representing 22 countries, by sharing data of these two waves.
Tcolombo Twin and Singleton Follow.up study (CoTaSS 2) is a collaboration between Institute for Research and Development and Kings College London, U K which is being conducted in Colombo CoTaSS 2 is the largest twin Study being conducted in South Asia to examine the overlap of depression and metabolic syndrome (MetS).
The Sleep sub-study was conducted within the Colombo Twin and Singleton Follow-up Study and determined the contribution of sleep and activity to the prevalence of metabolic syndrome and depression in Sri Lanka. It also aimed help to understand the potential for estimating the degree to which phenotypic correlations in sleep parameter are due to shared genetic or environmental factors as well.
Strong evidence exists which suggests associations between cardiovascular disease, diabetes and depression. The Colombo Twin and Singleton Study follow-up Study (CoTaSS 2) seeks to explore this in the Sri Lankan population and estimate the extent of overlapping genetic and environmental influences.
Examined the prevalence and heritability of a range of psychiatric disorders and gene-environmental interplay using a twin sample and a comparative singleton sample.