{"id":1074,"date":"2020-02-01T07:30:00","date_gmt":"2020-02-01T07:30:00","guid":{"rendered":"http:\/\/sltr.local\/?p=1074"},"modified":"2023-09-20T08:01:37","modified_gmt":"2023-09-20T08:01:37","slug":"the-relationship-between-independent-and-dependent-life-events-and-depression-symptoms-in-sri-lanka-a-twin-and-singleton-study","status":"publish","type":"post","link":"https:\/\/sltr.ird.lk\/si\/publication\/the-relationship-between-independent-and-dependent-life-events-and-depression-symptoms-in-sri-lanka-a-twin-and-singleton-study\/","title":{"rendered":"The relationship between independent and dependent life events and depression symptoms in Sri Lanka: a twin and singleton study"},"content":{"rendered":"\n<div id=\"publication-container\" class=\"wp-block-uagb-container uagb-block-37619af8 alignfull uagb-is-root-container\"><div class=\"uagb-container-inner-blocks-wrap\">\n<div class=\"wp-block-uagb-container uagb-block-8024b029\">\n<p><br>Helena M. S. Zavos, Bethan Dalton, Kaushalya Jayaweera, Lisa Harber-Aschan, Gayani Pannala, Anushka Adikari, Stephani L. Hatch, Sisira Siribaddana, Athula Sumathipala, Matthew Hotopf &amp; Fr\u00fchling V. Rijsdijk<\/p>\n\n\n<div class=\"publish-date wp-block-post-date\"><time datetime=\"2020-02-01T07:30:00+00:00\">February 2020<\/time><\/div>\n\n<div class=\"taxonomy-category wp-block-post-terms\"><a href=\"https:\/\/sltr.ird.lk\/si\/category\/publication\/papers\/\" rel=\"tag\">Papers<\/a><span class=\"wp-block-post-terms__separator\">, <\/span><a href=\"https:\/\/sltr.ird.lk\/si\/category\/publication\/\" rel=\"tag\">Publication<\/a><\/div>\n\n\n<p>Social Psychiatry and Psychiatric Epidemiology, Volume 55, Pages 237 \u2013 249<\/p>\n\n\n\n<p>doi:<a href=\"https:\/\/doi.org\/10.1007\/s00127-019-01765-z\"><\/a><a rel=\"noreferrer noopener\" href=\"https:\/\/doi.org\/10.1007\/s00127-019-01765-z\" target=\"_blank\">https:\/\/doi.org\/10.1007\/s00127-019-01765-z<\/a><\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-uagb-container uagb-block-33811260\">\n<h2 class=\"wp-block-heading has-text-align-left\">Abstract<\/h2>\n\n\n\n<p><strong>Purpose<\/strong><br>Life events have been associated with a variety of mental health conditions including depression. There is a scarcity of research in South Asia exploring the aetiology of independent and dependent life events and their relationship with depression symptoms. This study aimed, in a Sri Lankan population, to identify the socio-demographic correlates and genetic and environmental influences on independent and dependent life events and their relationship with depression.<\/p>\n\n\n\n<p><strong>Methods<\/strong><br>Questionnaire data came from the Colombo Twin and Singleton Follow-up Study, CoTaSS-2 (N\u2009=\u20093969), a population study of Sri Lankan twins and singletons. Lifetime-ever independent and dependent life events were measured using a questionnaire and depressive symptoms using the Revised Beck\u2019s Depression Inventory. Structural Equation Model-fitting analyses explored the genetic and environmental influences on life events and depression.<\/p>\n\n\n\n<p><strong>Results<\/strong><br>Living in a rural environment and financial hardship were associated with greater reporting of independent and dependent life events. Sex differences were evident in the aetiology of life events and depression symptoms. Independent and dependent life events, but not depression symptoms, were heritable in males. Independent life events and depression symptoms, but not dependent life events, were heritable in females. Non-shared environmental influences explained phenotypic associations between independent life events and depression symptoms in both males and females. Genetic and non-shared environmental influences explained the phenotypic associations between dependent life events and depression symptoms in males. Only non-shared environment explained the covariation between dependent life events and depression symptoms in females.<\/p>\n\n\n\n<p><strong>Conclusions<\/strong><br>Socio-demographic correlates of independent and dependent life events were similar to those reported in Western populations. Life events were associated with increased depression symptoms. Contrary to research in Western populations, we found that non-shared environmental, rather than genetic, influences explained much of the covariation between life events and depression symptoms. This suggests that whilst independent LEs may be heritable, the relationship is unlikely to be confounded by genetic influences and has significant implications for possible interventions for depression.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-uagb-container uagb-block-8b71c1c5\">\n<div class=\"wp-block-uagb-container uagb-block-68630121\">\n<div class=\"wp-block-uagb-container uagb-block-5e518491\">\n<p>Website:<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-uagb-container uagb-block-87ee0c4a\">\n<p><a href=\"https:\/\/link.springer.com\/article\/10.1007\/s00127-019-01765-z\">The relationship between independent and dependent life events and depression symptoms in Sri Lanka: a twin and singleton study | Social Psychiatry and Psychiatric Epidemiology (springer.com)<\/a><\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-uagb-container uagb-block-0fcdaf73\">\n<div class=\"wp-block-uagb-container uagb-block-aa1e510a\">\n<p>PDF:<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-uagb-container uagb-block-8d389701\">\n<p><a href=\"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00127-019-01765-z.pdf\">https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00127-019-01765-z.pdf<\/a><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Life events have been associated with a variety of mental health conditions including depression. There is a scarcity of research in South Asia exploring the aetiology of independent and dependent life events and their relationship with depression symptoms. This study aimed, in a Sri Lankan population, to identify the socio-demographic correlates and genetic and environmental influences on independent and dependent life events and their relationship with depression.<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_uag_custom_page_level_css":"","footnotes":""},"categories":[10,4],"tags":[],"class_list":["post-1074","post","type-post","status-publish","format-standard","hentry","category-papers","category-publication"],"translation":{"provider":"WPGlobus","version":"3.0.0","language":"si","enabled_languages":["en","si","ta"],"languages":{"en":{"title":true,"content":true,"excerpt":true},"si":{"title":false,"content":false,"excerpt":false},"ta":{"title":false,"content":false,"excerpt":false}}},"uagb_featured_image_src":{"full":false,"thumbnail":false,"medium":false,"medium_large":false,"large":false,"1536x1536":false,"2048x2048":false},"uagb_author_info":{"display_name":"admin","author_link":"https:\/\/sltr.ird.lk\/si\/author\/admin\/"},"uagb_comment_info":0,"uagb_excerpt":"Life events have been associated with a variety of mental health conditions including depression. There is a scarcity of research in South Asia exploring the aetiology of independent and dependent life events and their relationship with depression symptoms. This study aimed, in a Sri Lankan population, to identify the socio-demographic correlates and genetic and environmental&hellip;","_links":{"self":[{"href":"https:\/\/sltr.ird.lk\/si\/wp-json\/wp\/v2\/posts\/1074","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sltr.ird.lk\/si\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/sltr.ird.lk\/si\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/sltr.ird.lk\/si\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/sltr.ird.lk\/si\/wp-json\/wp\/v2\/comments?post=1074"}],"version-history":[{"count":11,"href":"https:\/\/sltr.ird.lk\/si\/wp-json\/wp\/v2\/posts\/1074\/revisions"}],"predecessor-version":[{"id":1989,"href":"https:\/\/sltr.ird.lk\/si\/wp-json\/wp\/v2\/posts\/1074\/revisions\/1989"}],"wp:attachment":[{"href":"https:\/\/sltr.ird.lk\/si\/wp-json\/wp\/v2\/media?parent=1074"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/sltr.ird.lk\/si\/wp-json\/wp\/v2\/categories?post=1074"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/sltr.ird.lk\/si\/wp-json\/wp\/v2\/tags?post=1074"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}