{"id":1032,"date":"2011-02-01T12:00:00","date_gmt":"2011-02-01T12:00:00","guid":{"rendered":"http:\/\/sltr.local\/?p=1032"},"modified":"2023-09-15T10:43:13","modified_gmt":"2023-09-15T10:43:13","slug":"genetic-and-environmental-contributions-to-the-overlap-between-psychological-fatigue-and-somatic-symptoms-a-twin-study-in-sri-lanka","status":"publish","type":"post","link":"https:\/\/sltr.ird.lk\/ta\/publication\/genetic-and-environmental-contributions-to-the-overlap-between-psychological-fatigue-and-somatic-symptoms-a-twin-study-in-sri-lanka\/","title":{"rendered":"Genetic and Environmental Contributions to the Overlap Between Psychological, Fatigue and Somatic Symptoms: A Twin Study in Sri Lanka"},"content":{"rendered":"\n<div id=\"publication-container\" class=\"wp-block-uagb-container uagb-block-acd07dbc alignfull uagb-is-root-container\"><div class=\"uagb-container-inner-blocks-wrap\">\n<div class=\"wp-block-uagb-container uagb-block-8024b029\">\n<p>Harriet A. Ball, Sisira H. Siribaddana, Athula Sumathipala, Yulia Kovas, Nick Glozier, Fr\u00fchling Rijsdijk, Peter McGuffin &amp; Matthew Hotopf<\/p>\n\n\n<div class=\"publish-date wp-block-post-date\"><time datetime=\"2011-02-01T12:00:00+00:00\">February 2011<\/time><\/div>\n\n<div class=\"taxonomy-category wp-block-post-terms\"><a href=\"https:\/\/sltr.ird.lk\/ta\/category\/publication\/papers\/\" rel=\"tag\">Papers<\/a><span class=\"wp-block-post-terms__separator\">, <\/span><a href=\"https:\/\/sltr.ird.lk\/ta\/category\/publication\/\" rel=\"tag\">Publication<\/a><\/div>\n\n\n<p>Twin Research and Human Genetics, Volume 14, Issue 1, Pages 53 \u2013 63<\/p>\n\n\n\n<p>doi:<a rel=\"noreferrer noopener\" href=\"https:\/\/doi.org\/10.1375\/twin.14.1.53\" target=\"_blank\">10.1375\/twin.14.1.53<\/a><\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-uagb-container uagb-block-33811260\">\n<h2 class=\"wp-block-heading has-text-align-left\">Abstract<\/h2>\n\n\n\n<p><em>Background:<\/em>&nbsp;Somatic symptoms often co-occur with psychological symptoms but this overlap is poorly understood. Some aspects of this overlap differ in the South Asian context, but it is not clear whether this is a reporting effect or an underlying difference in experienced illness.<\/p>\n\n\n\n<p><em>Methods:&nbsp;<\/em>Home interviews were administered to 4,024 twins randomly selected from a population-based twin register in the Colombo district of Sri Lanka (the CoTASS study). These included assessments of psychological, somatic and fatigue symptoms. The data were analyzed using factor analytic and quantitative genetic approaches.<\/p>\n\n\n\n<p><em>Results:<\/em>&nbsp;Confirmatory factor analysis showed that the symptoms from the three scales represented three separate dimensions, rather than all tapping into a single dimension. However, familial correlations among the data were most consistent with a common pathway model. This implies that a portion of the underlying vulnerability is common across psychological, fatigue and somatic symptoms. There were sex differences in the etiology of this model, with shared environmental and genetic influences playing different roles in men and women.<\/p>\n\n\n\n<p><em>Conclusions:<\/em>&nbsp;There is a complex etiological relationship between psychological, fatigue and somatic symptoms. This is similar in Sri Lanka to Western countries, but there may be a greater influence from the family environment, suggesting that care needs to be taken when generalizing research findings between countries. People who complain of certain fatigue or somatic symptoms may well also have psychological symptoms, or may have genetic or environmental vulnerabilities to such problems.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-uagb-container uagb-block-8b71c1c5\">\n<div class=\"wp-block-uagb-container uagb-block-68630121\">\n<div class=\"wp-block-uagb-container uagb-block-5e518491\">\n<p>Website:<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-uagb-container uagb-block-87ee0c4a\">\n<p><a href=\"https:\/\/www.cambridge.org\/core\/journals\/twin-research-and-human-genetics\/article\/genetic-and-environmental-contributions-to-the-overlap-between-psychological-fatigue-and-somatic-symptoms-a-twin-study-in-sri-lanka\/F4C334531B10C933E8A69F9279FE109E\">Genetic and Environmental Contributions to the Overlap Between Psychological, Fatigue and Somatic Symptoms: A Twin Study in Sri Lanka | Twin Research and Human Genetics | Cambridge Core<\/a><\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-uagb-container uagb-block-0fcdaf73\">\n<div class=\"wp-block-uagb-container uagb-block-aa1e510a\">\n<p>PDF:<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-uagb-container uagb-block-8d389701\">\n<p><a href=\"https:\/\/www.ird.lk\/wp-content\/uploads\/2015\/03\/Genetic-and-environmental-contributions-to-the-overlap-between-psychological-fatigue-and-somatic-symptoms.pdf\">https:\/\/www.ird.lk\/wp-content\/uploads\/2015\/03\/Genetic-and-environmental-contributions-to-the-overlap-between-psychological-fatigue-and-somatic-symptoms.pdf<\/a><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Somatic symptoms often co-occur with psychological symptoms but this overlap is poorly understood. Some aspects of this overlap differ in the South Asian context, but it is not clear whether this is a reporting effect or an underlying difference in experienced illness.<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_uag_custom_page_level_css":"","footnotes":""},"categories":[10,4],"tags":[],"class_list":["post-1032","post","type-post","status-publish","format-standard","hentry","category-papers","category-publication"],"translation":{"provider":"WPGlobus","version":"3.0.0","language":"ta","enabled_languages":["en","si","ta"],"languages":{"en":{"title":true,"content":true,"excerpt":true},"si":{"title":false,"content":false,"excerpt":false},"ta":{"title":false,"content":false,"excerpt":false}}},"uagb_featured_image_src":{"full":false,"thumbnail":false,"medium":false,"medium_large":false,"large":false,"1536x1536":false,"2048x2048":false},"uagb_author_info":{"display_name":"admin","author_link":"https:\/\/sltr.ird.lk\/ta\/author\/admin\/"},"uagb_comment_info":0,"uagb_excerpt":"Somatic symptoms often co-occur with psychological symptoms but this overlap is poorly understood. Some aspects of this overlap differ in the South Asian context, but it is not clear whether this is a reporting effect or an underlying difference in experienced illness.","_links":{"self":[{"href":"https:\/\/sltr.ird.lk\/ta\/wp-json\/wp\/v2\/posts\/1032","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sltr.ird.lk\/ta\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/sltr.ird.lk\/ta\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/sltr.ird.lk\/ta\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/sltr.ird.lk\/ta\/wp-json\/wp\/v2\/comments?post=1032"}],"version-history":[{"count":3,"href":"https:\/\/sltr.ird.lk\/ta\/wp-json\/wp\/v2\/posts\/1032\/revisions"}],"predecessor-version":[{"id":1578,"href":"https:\/\/sltr.ird.lk\/ta\/wp-json\/wp\/v2\/posts\/1032\/revisions\/1578"}],"wp:attachment":[{"href":"https:\/\/sltr.ird.lk\/ta\/wp-json\/wp\/v2\/media?parent=1032"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/sltr.ird.lk\/ta\/wp-json\/wp\/v2\/categories?post=1032"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/sltr.ird.lk\/ta\/wp-json\/wp\/v2\/tags?post=1032"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}